Thursday, May 3, 2007

Dysplastic Nevi Syndrome

Dysplastic nevi are atypical moles, which, although benign, resemble melanoma and indicate an increased risk. Those who have dysplastic nevi and a family history of melanoma have a 200-fold increase in risk of developing melanoma. Those who have dysplastic nevi but no family history of melanoma also have up to fifteen times greater risk of developing melanoma than the general population.
Research has shown that the risk of melanoma in members of families affected by atypical mole (dysplastic nevus) syndrome is 49 percent in persons 1-50 years old and 82 percent by age 72. People with “classic atypical mole syndrome” have the following three characteristics:
100 or more moles
One or more moles greater than 8mm (1/3 inch) in diameter
One or more moles that look atypical
If your doctor suspects the presence of dysplastic nevi, one or more moles may be removed by “excision biopsy,” a minor surgical procedure, for microscopic examination. It is not necessary to remove all dysplastic nevi. If moles show change or signs of melanoma, or if new moles appear after age 40, they may be considered for removal by your physician.

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